Domenico's daughter Rose Marie marries the son of the head of the Santadio family fueling the crime families feud. Domenico Clericuzio, the family Patriarch exacts revenge on the Santadio family by ordering the execution of the entire Santadio family, including his new son-in-law on Rose Marie Clericuzio's wedding night. After her brief wedding night, Rose Marie is filled with grief and learns she is pregnant. She gives birth to her son Dante and as he grows, he is instilled with an evident hatred for his grandfather. In turn, the family becomes increasingly aware of his taste for blood.

A vengeful murder and a corrupt cop figure into Dante's scheme to devastate Cross and lead the Clericuzio family back to its glory.