Yakumo Fugii, an ordinary Japanese student, inherits the care of Pai, a young girl from Nepal, from his dying archaeologist father. But Pai is more than she innocently appears to be. She is the last of a vanished magical race known as the Sanjiyan Unkara, or Triclops, and is in a desperate hunt against the forces of darkness to find the Ningen no Zou (Statue of Humanity) to turn her human. Yakumo nearly dies in a fight against a demon and to save him, Pai turns him into a Wu, a zombie bound to her service who cannot die. Yakumo and Pai travel to Hong Hong to meet with Ling Ling Lee, a colleague of his father's, to track down the statue. But, the demons of the dark lord Kaiyan Wang are already there to retrieve it...whatever the cost.

Yakumo and Pai return to Japan from Hong Kong after the Statue of Humanity disappears from the mysterious Mrs. Huang's mansion. Yakumo returns to school and his friends in the hopes of resuming a normal life. But nothing is normal when you're an undead zombie bound to a magical being and demons start attacking your schoolmates on the playground!

Yakumo, Pai, and the crew of Monster Buster, Inc celebrate their recapture of the statue at Madame Huang's estate, but the party is spoiled by a gruesome challenge delivered by a powerful Wu of Kaiyan Wang's. Pai meets the Wu for a showdown at Aberdeen Harbor and half the harbor is destroyed in the aftermath. How will Yakumo continue on without the anchor of his life?