阴云密布的童守高中迎来新的学期，神神叨叨的新老师鵺野鸣介（丸山隆平 饰）和帅气迷人的玉藻（速水重道 饰）走马上任。鸣介因为童年的经历，拥有常人无法想象的能力，但是在众人面前他总是一副怪力乱神毫不可靠的样子。而他的学生立野广（中川大志 饰）、木村克也（吉泽亮 饰）、稻叶乡子（松井爱莉 饰）、细川美树则是一群问题多多却各有优点的少男少女。鸣介喜欢美丽古板的女老师高桥律子（桐谷美玲 饰），同时又被多年前救过的雪女（知英 饰）所纠缠，生活可谓一团糟。更令人应接不暇的是，各类可怕的妖怪交替出现在童守町，鸣介只有用他的鬼手保护可爱的学生们……

　　本片根据同名漫画改编。

Meisuke Nueno (Ryuhei Maruyama) is the homeroom teacher of a 2nd grade 3 class in high school. He is referred to as Nube. He sometimes carries himself as an idiot, but he does care about his students a lot. He also has a hidden side. Meisuke Nueno has a demon's hand. He solves monstrous case and fights desperately to save students from monsters.

아이들을 요괴나 악령으로 부터 보호하기 위해 악마의 손을 가진 고등학교 교사 누베가 퇴치하는 드라마