After receiving a cryptic, urgent distress call from Dr. Beverly Crusher, Admiral Jean-Luc Picard enlists help from generations old and new to embark on one final adventure: a daring mission that will change Starfleet, and his old crew forever.

Aided by Seven of Nine and the crew of the U.S.S. Titan, Picard makes a shocking discovery that will alter his life forever – and puts him on a collision course with the most cunning enemy he’s ever encountered. Meanwhile, Raffi races to track a catastrophic weapon – and collides with a familiar ally.

Picard grapples with an explosive, life-altering revelation, while the Titan and her crew try to outmaneuver a relentless Vadic in a lethal game of nautical cat and mouse. Meanwhile, Raffi and Worf uncover a nefarious plot from a vengeful enemy Starfleet has long since forgotten.

Caught by Starfleet and facing court martial, paranoia grows as Picard struggles to uncover whether a prodigal crewman from his past has returned as an ally – or an enemy hellbent on destroying them all.

Now on the run, Picard and the skeleton crew of the USS Titan must break into Starfleet's most top-secret facility to expose a plot that could destroy the Federation. Picard must turn to the only soul in the galaxy who can help: an old friend.

Crippled, cornered, and out of options, Picard stages a gambit to trap Vadic and reveal her true motive – a gamble that puts the Titan in the crosshairs and forces Picard and Beverly to question every moral code they’ve ever held.

Vadic forces Picard to make an impossible choice: deliver what he can never give... or watch his crew perish. Their only salvation lies in the mind of an old friend and old foe.

A devastating revelation about Jack alters the course of Picard’s life forever – and uncovers a truth that threatens every soul in the Federation. The final battle begins as Picard and his crew race to save the galaxy from annihilation – but not without a gut-wrenching cost.

In a desperate last stand, Jean-Luc Picard and generations of crews both old and new fight together to save the galaxy from the greatest threat they’ve ever faced as the saga of Star Trek: The Next Generation comes to a thrilling, epic conclusion.