An Amber Alert rings out at St. Mary's, but unbeknownst to the nurses the perpetrator and the abducted child are in the hospital.

Hospitals are no stranger to the things that keep us up at night or the secrets we keep, as the strange gets stranger on the night shift at St Mary's.

A high-profile surgical case brings Grace and Ashley into conflict over whether or not the surgeon is capable of performing the surgery.

When a tragic accident at a concert suddenly puts St Mary's in a Code Orange, our nurses will realise how important it is to have someone in your corner, because no one should be alone.

Ghosts from the past make a day at St Mary's especially trying for our nurses as they're each confronted by people or things they tried to leave behind.

It's Nursing Week and St Mary's nurses and patients alike are confronted by the fact that everyone has a hidden side, and that nothing can be taken at face value.

Assigned to the Burn Unit, Naz and Grace are pushed to their limits as Nurses - and friends - when they disagree over how to deal with a critically burned patient who's in danger of losing his will to live.

With uncertainty in their personal lives and a pandemic on the horizon, our nurses each deal with people longing for wishes to come true for their health or their loved ones, but they're wishes that may not be in the power of a nurse to grant.

With both patients and the whole Healthcare system on the brink of tragic events, the St Mary's nursing team must put their own struggles aside to help those with everything on the line.